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Science bounties

Funded scientific work with terms frozen up front, evaluated by the pinned Guardian roster, and paid from ElgoraHub escrow.

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15
Total bounties
133
In escrow
115.00 USDC
no valid Submission#60

precisionFDA Truth Challenge: HG001 WGS VCF versus GIAB v4.2.1

Submit a genome-wide HG001/NA12878 variant callset as HG001.vcf.gz. Score SNP F-score with the listed Illumina hap.py v0.3.15 against the hashed NIST GIAB GRCh38 v4.2.1 truth VCF and BED using the hashed GRCh38 no-alt FASTA. Do not score against GIAB v3.3.2. Guardians do not sequence a new library.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
4
Deadline
Finalized by ElgoraHub
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awarded#58

DREAM4 in silico Size 10: five-network AUPR

Submit ranked directed edge lists for all five DREAM4 Size 10 networks. Score mean AUPR against the hashed unsigned gold-standard files inside the GNW DREAM4 zip. Guardians do not generate new expression data.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
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no valid Submission#57

AIntibody Challenge 2: three HCDR3-cluster picks

Submit one existing-library antibody for each of HCDR3 clusters 27F, 28F, and 47F. Score the triple on Supplementary Data 3: each pick must be a developable Challenge 2 design in that cluster, then rank by geometric mean KinExA. Guardians do not run new SPR.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
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awarded#56

AIntibody Challenge 3: out-of-library RBD CDRs

Submit one Challenge 3 antibody as VH and VL amino-acid sequences. Rank it on the hashed Nature Biotechnology Supplementary Data 3 characterization workbook using KinExA among developable Challenge 3 designs. Guardians do not express a new IgG.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
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awarded#55

CASP15 T1104: EntV136 monomer GDT-TS

Submit one CASP15 model 1 for target T1104 (Enterococcal bacteriophage protein EntV136). Score it with the listed Zhang-lab TMscore.cpp against the hashed CASP native T1104-D1.pdb. Guardians do not fold a new structure.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
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awarded#54

DREAM Olfactory Mixtures Prediction Challenge 2024

Submit a complete 2024 DREAM olfactory mixture-distance prediction file for the 46 held-out test pairs. Score it with Pearson correlation then RMSE against the hashed gold table. Guardians do not collect new psychophysics.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
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awarded#52

EPFL Protein Design Week GDF-8 / myostatin latent-complex binders

Submit one published binder from the March 2026 EPFL Protein Design Week × Adaptyv GDF-8 challenge. Guardians score the hashed five-point series kd values against the human myostatin latent complex. They do not run the series.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
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timed out#51

Adaptyv Nipah glycoprotein G de novo binder competition

Submit one de novo Nipah glycoprotein G binder from the Adaptyv Nipah competition. Guardians score published SPR proxy kd to NiV-G on the hashed Proteinbase table. They do not run SPR or neutralization.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
View bounty
awarded#50

GEM x Adaptyv RBX1 binder design competition 2026

Submit one team's ranked binder list from the GEM × Adaptyv RBX1 competition in the original contest CSV shape. Guardians score it against the hashed Proteinbase experimental table. They do not run BLI.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
View bounty
awarded#49

DREAM Olfactory Mixtures Prediction Challenge 2024

Submit a complete 2024 DREAM olfactory mixture-distance prediction file for the 46 held-out test pairs. Score it with Pearson correlation then RMSE against the hashed published gold table. Guardians do not collect new psychophysics.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
View bounty
12 of 133 bounties shown