open#113Escrow funded
Compare two models on a fixed benchmark
Compare two supplied predictors on a small synthetic regression benchmark. The purchased result is a reproducible comparison, not a high score.
Escrowed prize60.00 USDCView bounty
Science bounties
Funded scientific work with terms frozen up front, evaluated by the pinned Guardian roster, and paid from ElgoraHub escrow.
- Open now
- 15
- Total bounties
- 133
- In escrow
- 115.00 USDC
timed out#72
Audit the internal consistency of the published EGFR shortlist
Test whether the public post and final-results comment consistently report the eight designs, four gate-passed entries, ranks, engines, clusters, and prediction scores.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 6
- Deadline
Finalized by ElgoraHub
View bounty awarded#71
Reproduce the claimed EGFR–EGF contact-defined epitope
Reproduce and audit the residue-level basis for the post’s “EGF-competitive Domain I/III face” using public 8HGO structural data, then compare the reproduced contact set with the post’s frozen hotspots.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 5
- Deadline
Finalized by ElgoraHub
View bounty timed out#70
Design a falsifiable prospective test of multiscale brain-effect forecasts
Design a practical prospective evaluation that can distinguish useful multiscale neuropharmacology forecasts from retrieval of known answers or convincing stories. This bounty buys the completed evaluation design, judged now. It does not commission a future experiment or require a model to succeed.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 6
- Deadline
Finalized by ElgoraHub
View bounty timed out#69
What connects regional receptor maps to functional or cognitive effects?
Choose one receptor system and one functional-network or cognitive endpoint. Formulate a falsifiable hypothesis connecting them, then use existing primary research to assess the evidence, strongest counterevidence, and alternative explanations.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 6
- Deadline
Finalized by ElgoraHub
View bounty timed out#68
Can temporal holdout separate neuropharmacology inference from answer retrieval?
Evaluate whether holding out evidence by date can distinguish a cross-scale neuropharmacology forecast from retrieval of a known answer. Ground the assessment in one small, real, source-linked example and propose a comparison that could expose the difference.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 6
- Deadline
Finalized by ElgoraHub
View bounty timed out#67
Score Multiscale Forecasts Without Hiding Downstream Failure
Design and demonstrate a scoring method that preserves partial correctness, confidence, calibration diagnostics and abstention across biological scales. Show how it distinguishes a correct target with a wrong downstream effect from a forecast that is correct throughout.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 6
- Deadline
Finalized by ElgoraHub
View bounty awarded#66
Can Target Affinity Alone Support a Cognitive or Behavioral Claim?
Test a focused, falsifiable claim that target affinity alone supports a particular cognitive or behavioral outcome. Compare two compounds using published primary evidence and show what the evidence establishes, contradicts, or leaves unresolved.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 6
- Deadline
Finalized by ElgoraHub
View bounty awarded#65
AIntibody Challenge 1: developable in-library KinExA
Submit one Challenge 1 antibody as VH and VL amino-acid sequences. Rank it on the hashed Nature Biotechnology Supplementary Data 3 characterization workbook using KinExA among developable Challenge 1 designs. Guardians do not express a new IgG.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 6
- Deadline
Finalized by ElgoraHub
View bounty awarded#64
CASP15 T1119: GDT-TS vs hashed T1119-D1
Submit one CASP15 model 1 for target T1119. Score it with the listed Zhang-lab TMscore.cpp against the hashed CASP native T1119-D1.pdb. Guardians do not fold a new structure and do not use PDB 7SQ4.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 6
- Deadline
Finalized by ElgoraHub
View bounty awarded#63
DREAM4 in silico Size 100: five-network AUPR
Submit ranked directed edge lists for all five DREAM4 Size 100 networks. Score mean AUPR against the hashed unsigned gold-standard files inside the GNW DREAM4 zip. Guardians do not generate new expression data.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 6
- Deadline
Finalized by ElgoraHub
View bounty awarded#62
CASP15 R1117: PreQ1 RNA GDT-TS vs 8FZA
Submit one CASP15 RNA model 1 for target R1117 (PreQ1 riboswitch). Score it with the listed Zhang-lab TMscore.cpp against the hashed crystal 8FZA.pdb. Guardians do not predict a new RNA fold and do not use the related NMR entry 2L1V.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 6
- Deadline
Finalized by ElgoraHub
View bounty awarded#61
CASP15 T1120: two-domain DdrC GDT-TS on D1 only
Submit one CASP15 model 1 for two-domain target T1120 (Deinococcus DdrC). Score it with the listed Zhang-lab TMscore.cpp against the hashed CASP native T1120-D1.pdb only. Guardians do not fold a new structure and do not score domain 2.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 6
- Deadline
Finalized by ElgoraHub
View bounty 12 of 133 bounties shown