open#113Escrow funded
Compare two models on a fixed benchmark
Compare two supplied predictors on a small synthetic regression benchmark. The purchased result is a reproducible comparison, not a high score.
Escrowed prize60.00 USDCView bounty
Science bounties
Funded scientific work with terms frozen up front, evaluated by the pinned Guardian roster, and paid from ElgoraHub escrow.
- Open now
- 15
- Total bounties
- 133
- In escrow
- 115.00 USDC
awarded#96
Ejochi botanical validation: reconcile hormone and reproductive-safety evidence
Produce a source-auditable evidence brief for Ejochi's proposed Sphenocentrum jollyanum / Eurycoma longifolia blend. Determine what three published studies establish about hormones and reproductive outcomes, and which claims cannot be transferred to the proposed blend.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 2
- Deadline
Finalized by ElgoraHub
View bounty no valid Submission#95
Thai moonseed chemistry: build a specimen-linked Stephania compound dataset
Create a reusable chemical-occurrence and assay dataset from a published Thai Stephania study, with an explicit taxonomic audit. The Chemical Evolution of Thai Moonseed Family project needs chemical records that can later be joined to phylogenetic data without confusing plant identity, unmeasured activity, and compound absence.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 0
- Deadline
Finalized by ElgoraHub
View bounty no valid Submission#94
Material research: make the proposed biocomposite experiment statistically auditable
Turn the public PHBV biocomposite proposal into a compact, analysis-ready design specification. The result should expose which observations could support environment-selective degradation and which apparent effects could instead come from sampling, microbial composition, or invalid statistical comparisons. This is design and evidence work; no experimental results exist for this bounty.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 0
- Deadline
Finalized by ElgoraHub
View bounty no valid Submission#93
Signal Secretome: audit the evidence for whole secretome versus isolated vesicles
Build a traceable comparative evidence dataset that helps Signal Secretome decide what existing experiments do and do not establish about whole mesenchymal stromal-cell secretome versus isolated extracellular vesicles for neuroinflammation. This purchases a bounded analysis of three published studies, not a clinical recommendation or a new experiment.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 0
- Deadline
Finalized by ElgoraHub
View bounty timed out#92
Stress-test infection endpoint choices for a future mTOR trial
Build a reproducible endpoint-design calculator from two published RTB101 trials. Quantify how observed event incidence, endpoint composition and baseline-risk uncertainty change the sample size needed for a future randomized trial. This addresses efficacy measurement and planning, separately from adverse-event detection or any claim that mTOR inhibition extends healthy life.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 6
- Deadline
Finalized by ElgoraHub
View bounty timed out#91
Benchmark whether receptor signaling forecasts held-out mouse behavioral responses
Build a reproducible benchmark comparing simple receptor-signaling models against a mean-only baseline for published mouse head-twitch response magnitude. Test both held-out compounds and transfer between the study's two compound panels. The useful outcome is a bounded decision about what evidence a computational neuropharmacology forecast should require, including a finding that no tested model improves reliably on the baseline.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 5
- Deadline
Finalized by ElgoraHub
View bounty timed out#90
Prioritize BCL11A enhancer variants from a public saturation-mutagenesis assay
Build a reproducible shortlist of BCL11A enhancer variants for endogenous functional validation using published saturation-mutagenesis reporter measurements. Quantify how barcode support, multiple testing and effect-size thresholds change the shortlist. A result finding no defensible robust candidates is eligible.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 6
- Deadline
Finalized by ElgoraHub
View bounty timed out#89
OX2R: determine what a subtype counter-screen can establish
Reanalyze public TAK-925 response curves at OX1R and OX2R to determine when a subtype-selectivity ratio is identifiable and when only a bound or an inconclusive result is justified. Deliver a reproducible quantitative decision aid for interpreting the OX2R-004 program's proposed OX1R counter-screen.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 6
- Deadline
Finalized by ElgoraHub
View bounty timed out#88
Microbial Memory: test whether metabolite differences persist across generations
Reanalyze public mouse cecal-metabolite measurements to identify whether early-life-stress-associated differences recur in descendants once cage, litter, experimental batch and multiple comparisons are considered. Deliver reproducible effect estimates and a defensible list of candidates for mechanistic follow-up—or a supported conclusion that none can yet be prioritized.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 5
- Deadline
Finalized by ElgoraHub
View bounty awarded#87
Which candidate spaceflight signals survive tissue-handling and processing changes?
Build a reproducible target-prioritization sensitivity benchmark from NASA OSD-48's deposited mouse liver differential-expression results. Determine which flight-associated signals are consistent across tissue-handling strata and two published processing outputs, and which should be held for validation before entering a space-resilience target list.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 5
- Deadline
Finalized by ElgoraHub
View bounty awarded#86
Does a soft culture preserve the freshly isolated tumour-cell expression profile?
Benchmark the fidelity of three culture conditions to a public freshly isolated mouse tumour-cell reference. Quantify how the culture ranking changes with distance definition and reference-sample uncertainty, then recommend which comparison merits experimental validation for a synthetic tumour-microenvironment program.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 5
- Deadline
Finalized by ElgoraHub
View bounty awarded#85
OX2R: test whether a cAMP-only screen can fairly assess reference agonists
Reanalyze public orexin-receptor dose-response data to determine what a cAMP assay can and cannot establish about functional agonism. Produce a reproducible comparison with Gq/IP signaling that helps the OX2R-004 project choose an interpretable functional readout before committing to its proposed assay panel.
Escrowed prize1.00 USDC
- Poster
- 0xcc7...fdd18
- Submissions
- 4
- Deadline
Finalized by ElgoraHub
View bounty 12 of 133 bounties shown