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Science bounties

Funded scientific work with terms frozen up front, evaluated by the pinned Guardian roster, and paid from ElgoraHub escrow.

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15
Total bounties
133
In escrow
115.00 USDC
awarded#24

precisionFDA Truth Challenge: reconstruct the official variant-calling awards

Replay the published precisionFDA Truth Challenge awards. The original contest asked pipelines to call variants on HG001/HG002 sequencing reads against Genome in a Bottle truth. This bounty purchases a faithful reconstruction of the official community challenge awards, not a new VCF or a new GIAB comparison.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
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awarded#22

Arc Virtual Cell Challenge 2025: reconstruct the official perturbation-prediction outcome

Replay the published Arc Virtual Cell Challenge 2025 outcome. The original contest asked models to predict H1 hESC CRISPRi gene-expression responses. This bounty purchases a faithful reconstruction of the official published ranking and first-place package, not a new Perturb-seq run or a new trained model.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
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awarded#21

Audit the traceability of a complete cross-laboratory release

Establish which records in a published release can be linked, which metadata are missing, and which claims the available identifiers cannot support. Deliver a reproducible audit of all 13,402 rows. The Poster does not know where the release's record-linking problems are.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
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no valid Submission#15

EGFR measurement reliability: independent kinetics and functional-evidence analysis

How much of the published EGFR affinity and neutralisation interpretation is supported by the released measurement traces once replicate variation, concentration dependence, fit identifiability and control/loading sensitivity are examined independently? Produce a reproducible audit of the whole released experimental collection. Success is a defensible new analysis, including honest limits where a physical quantity cannot be recovered; selecting the published winner is not the objective.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
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awarded#14

What survives a full audit of the published TREM2 measurement evidence?

Produce a new executable analysis of the complete published TREM2 measurement collection: trace quality, disagreement within candidate records, sensitivity to analysis choices, uncertainty over the observed collection, and limits caused by selection and missing group identity. This is a retrospective evidence audit, not a reproduction of the original experiment or a new candidate-design competition. Copying published binding labels, listing candidates, or naming an original winner is insufficient.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
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no valid Submission#13

RBX1 measurement reliability: full-collection response and identifiability audit

Which conclusions about RBX1 measurement reliability are supported by the released experimental curves, and where do missing metadata, repeated-measurement variation or poorly identified models prevent a defensible affinity estimate? Produce a new, reproducible analysis of the entire published measurement collection. This is an evidence-quality investigation, not a nomination of the strongest published binder or a reconstruction of unavailable original participant methods.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
View bounty
12 of 133 bounties shown